AUTOLOGOUS HAEMATOPOIETIC STEM CELL TRANSPLANTATION IN MS

Autologous haematopoietic stem cell transplantation in juvenile idiopathic arthritis.

Autologous haematopoietic stem cell transplantation for neurological diseases

Neuroinflammatory diseases such as multiple sclerosis, neuromyelitis optica, chronic inflammatory demyelinating polyneuropathy and myasthenia gravis are leading causes of physical disability in people of working age. In the last decades significant therapeutic advances have been made that can ameliorate the disease course. Nevertheless, many affected will continue to deteriorate despite treatme...

Lymphocyte reconstitution following autologous stem cell transplantation for progressive MS

BACKGROUND Autologous stem cell transplantation (ASCT) for progressive multiple sclerosis (MS) may reset the immune repertoire. OBJECTIVE The objective of this paper is to analyse lymphocyte recovery in patients with progressive MS treated with ASCT. METHODS Patients with progressive MS not responding to conventional treatment underwent ASCT following conditioning with high-dose cyclophosph...

Hodgkin’s Lymphoma Occurring Secondary to Autologous Stem Cell Transplantation in Plasma Cell Leukemia; A Case Report

Survival of patients with multiple myeloma has improved substantially because of availability of new therapies including autotransplants, immunomodulating drugs and proteasome-inhibitors. Second primary cancers have emerged as an important determinant of morbidity and mortality among cancer survivors. Even though there is an increased risk of new cancers of the lymphoreticular and haematopoetic...

Developments in haematopoietic stem cell transplantation.

Haematopoietic stem cell transplantation remains the treatment of choice for a variety of benign and malignant blood disorders.1 In this modality Haematopoietic stem cell transplantation is the intravenous infusion of haematopoietic stem and progenitor cells to re-establish marrow function in patients with damaged or defective marrow. The procedure is called Bone Marrow Transplantation (BMT) if...